A new report exploring the potential for the Pacific Northwest to stake its claim as the global leader in responsible AI offers a paradoxical view. The Cascadia region, which includes Seattle, Portland and Vancouver, B.C., is described as a proven, promising player in the sphere — but with significant risks that threaten its success.

“We created companies that transformed global commerce,” writes former Gov. Chris Gregoire in a forward to the document. “Now we have the chance to add another chapter — one where Cascadia becomes the world’s standard-bearer for innovation that uplifts both people and planet.”

The Cascadia Innovation Corridor, which Gregoire chairs, released the report this morning as it kicks off its two-day conference. The economic advocacy group’s eighth annual event is being held in Seattle.

The study is built on an analysis by the Boston Consulting Group that ranks Cascadia’s three metro areas against 15 comparable regions in the U.S. and Canada for their economic competitiveness, including livability, workforce, and business and innovation climate. Seattle came in fourth behind Boston, Austin and Raleigh, while Portland ranked 13th and Vancouver 14th.

Over the past decade, the region’s gross domestic product and populations have both grown significantly, and when combined, their economies approach the 18th largest in the world.

Cascadia’s strengths, the report explains, include tech engines such as cloud giants Microsoft and Amazon in Washington, silicon chip manufacturing in Oregon, and quantum innovation in Vancouver, as well as academic excellence from the University of Washington, University of British Columbia and Oregon State University.

But as time goes on and as business and civic leaders aim for the prize of AI dominance, cracks in the system are increasingly troubling.

• Business costs are rising and there are mounting regulatory concerns — but it’s a tricky picture. Seattle, for example, often turns to B&O and headcount taxes to cover costs, while the state struggles to balance budgets in the absence of an income tax.
• Housing affordability is continuing to decline for many residents in these metro areas.
• Skilled tech workers are leaving Portland, in particular, and Seattle relies heavily on foreign workers receiving H1-B visas, which are less certain under the Trump administration.
• The clean, affordable energy that was once abundant in the Pacific Northwest is decreasingly available as droughts reduce river flows that drive hydropower dams and electricity demand increases with rapid data center growth.

The report notes that multiple regions around the U.S. and Canada have created AI-focused hubs with hundreds of millions of dollars in public and private funding to bolster their hold on the sector.

New Jersey has a half-billion dollar “AI Moonshot” program including tax incentives and public-worker AI training programs; New York’s “Empire AI Consortium” has an AI computing training center at the University of Buffalo and startup supports; and California has a public-private task force to increase AI adoption within government services and connecting tech leaders with state agencies.

For its part, Seattle Mayor Bruce Harrell announced a “responsible AI plan” this fall that provides guidelines for the municipality’s use of artificial intelligence and its support of the AI tech sector as an economic driver, which includes the earlier launches of the startup-focused AI House and Foundations.

But what the region really needs to succeed is a collaborative effort tapping all of the metro areas’ assets.

“For Cascadia, the lesson is clear: without a coordinated strategy that links our strengths in cloud computing, semiconductors, and research, we risk falling behind,” states the Cascadia Innovation Corridor report. “Acting together, we can position Cascadia not just to keep pace, but to lead.”

Hundreds of global leaders gathered in the Pacific Northwest this week for the inaugural One Ocean Week Seattle, a maritime conference with dozens of events that brought together company executives, government officials and advocates charting paths toward cleaner shipping, sustainable fishing and ocean conservation.

The conference, organized by Washington Maritime Blue, was anchored by Wednesday’s One Ocean Summit, where leaders from global companies with Seattle ties discussed their climate progress and the challenges of deploying sustainable technologies.

Seattle-based SSA Marine, a global marine terminal operator, has 200 locations worldwide, moving cargo from ships to terminals and onto trains and trucks. The company has carbon emissions targets and is working to shift from gas and diesel to electrical power for the machines moving moving the cargo, but the move requires juggling sometimes competing factors.

“If you have a piece of electrical equipment, you have to think about charging time that’s required in between shifts, and when can you actually fit it in there?” said Meghan Weinman, SSA Marine’s vice president of sustainability. “One of those big pieces of innovation that we really have to think about is the overlay of technology, labor planning, and can it do the job that we need it to do.”

Corvus Energy is a Norwegian clean shipping company with Seattle offices and a manufacturing facility in Bellingham, Wash. The business is helping vessels go electric with its maritime battery technologies, serving ferries, cruise ships, tugs, cranes and fishing boats.

It’s an evolving sector and the company spends up to 15% of its annual revenue on research and development to fine-tune its technology to meet demanding oceanic conditions.

“It is totally different to operate a battery in an EV versus a maritime setting,” said Corvus CEO Fredrik Witte. “For an EV, you’re traveling three, four hours a day, maybe. But in a maritime setting, you’re potentially operating 24/7.”

Seattle’s Trident Seafoods operates fishing boats and onshore production facilities, including the largest seafood processing plant in North America in Akutan, Alaska. While seafood typically has a much lower carbon footprint than beef, pork or dairy, the company wants to reduce the climate impacts associated with its operations.

But Paul Doremus, Trident Seafoods’ vice president of policy and sustainability, pointed to a hard reality: the company competes directly with Russian and Chinese seafood companies that are doing business under less stringent environmental regulations.

He said the seafood sector — “which has been kind of famously fragmented, small, fairly scrappy” — needs to come together to collectively make improvements.

Doremus applauded events like One Ocean Week Seattle for gathering maritime interests to draw attention and capital toward “sustainable use of the ocean for the benefit of local communities, regional and national.”

“I think that’s the next wave,” he said.

Collaboration and innovation

The call for collaboration echoed throughout the One Ocean Summit, which also featured former NOAA Administrator Jane Lubchenco, United Nations officials, and Norway’s ambassador to the U.S.

Washington Lt. Gov. Denny Heck gave a welcome address, highlighting the state’s maritime economy while calling out threats from plastic pollution, undersea noise, and environmental degradation.

“To face these challenges, we will need to develop new technologies and strengthen our institutions,” Heck said. “It will require sustainable fuel storage, habitat restoration, quiet propulsion and so many other inventions and innovations. But more importantly, it will require the dedication and teamwork of thousands of people.”

The message was reinforced by Haakon Vatle, leader of the One Ocean Expedition, which is sailing a 111-year-old Norwegian tall ship across the globe. The ship, named the Statsraad Lehmkuhl, was moored just outside Bell Harbor International Conference Center during the event.

“The role of our ship is to create attention and share knowledge of the crucial role of the ocean for a sustainable future,” Vatle said. “We’re going to use a ship to reduce the gap between science and the public — get the people we need for the ocean we want. We cannot save the ocean alone.”

Editor’s note: GeekWire reporter Lisa Stiffler was the volunteer emcee of the One Ocean Summit.

Award-winning immunologist ​​Susan Kaech is the new executive vice president of the Allen Institute’s Immunology Moonshot, an initiative that aims to understand the immune system’s role in human health and disease.

Kaech currently leads the NOMIS Center for Immunobiology and Microbial Pathogenesis at the Salk Institute for Biological Studies and will join the Allen Institute in January.

“The appointment comes at a critical time in bioscience when the immune system is regarded as the cornerstone of all diseases and understanding its foundational principles is vital to unlocking new treatments and therapies,” the institute said in a statement.

Kaech’s research includes the investigation of how the immune system remembers infections to develop immunity, T-cell communications, and the role of metabolism in the immune system’s fight against cancer.

—  Seattle RFID company Impinj named Arthur Valdez Jr. to its board of directors.

Valdez recently left the role of executive VP of global supply chain and customer solutions at Starbucks and his career includes leadership roles at Amazon, Target and elsewhere.

“Arthur’s expertise transforming and optimizing strategic supply chain and logistics networks for large consumer-facing companies will be invaluable as we continue to advance our vision of connecting every thing,” said Impinj CEO Chris Diorio in a statement.

— Jason Bennett has taken a new role at Amazon Web Services, shifting from VP of U.S. enterprise to VP of worldwide startups and venture capital. Bennett has been with the company for more than 17 years.

On LinkedIn Bennett shared his fondness for working with startups and said he was eager to return to a position serving that community.

“I’m energized by the opportunity to work alongside our teams to support a thriving startup ecosystem — from founders and VCs, to accelerators, and the broader innovation community,” he said, adding that the work “has a lasting impact on the direction of industries and the future of AI.”

— NuScale Power named James Canafax as chief legal officer and corporate secretary. The Tigard, Ore.-based nuclear energy company is developing small modular reactors.

Canafax has decades of legal experience and joins NuScale from Maritime Partners. Past positions include executive leadership at BWX Technologies, which supplies nuclear components and services.

“[Canafax’s] extensive experience in the nuclear industry, deep familiarity with the regulatory environment and track record of guiding organizations through key growth periods make him uniquely suited to support NuScale at this important moment for our company,” CEO John Hopkins said in statement.

— Seattle entrepreneur Elvis Dieguez is now VP of data science, analytics and platforms for the healthcare startup hims & hers. Diegeuz joins the company from symphonie, a Seattle e-commerce marketing platform where he was CEO and co-founder. He was previously at Amazon for more than four years working in business analytics and as a senior manager.

Hims & hers offers a telehealth platform for conditions including sexual health, hair loss, mental health, skincare and weight loss.

“I look forward to leading and working with a ~70 person team who’ve been working hard to make the #healthcare system work for all Americans,” Dieguez said on LinkedIn.

— Biotech startup Synthesize Bio named Ariel Brumbaugh as senior director of business development. In the role, Brumbaugh will help the company partner with biopharma companies interested in using Synthesize’s AI-based research platform to accelerate and de-risk drug development.

Seattle’s Synthesize Bio was founded by leaders from Fred Hutchinson Cancer Center. Last month it announced $10 million in funding from Madrona.

Brumbaugh joined the startup from the San Francisco biotech company Gladstone Institutes.

— Sophie Brougham is director of philanthropic operations for the recently launched Clean Economy Project. Nicknamed CleanEcon, the effort includes past employees of the Bill Gates-led Breakthrough Energy and is a policy and advocacy platform promoting clean power.

Prior to Breakthrough, Brougham was with the Paul Allen holding company Vulcan (now known as Vale Group) for more than a decade, where she was a senior manager and led programs including philanthropic and grants management.

— Seattle’s Jake Laes is now executive director of AI Tinkerers, a global network of AI engineers and builders. Laes joined the group from Deel, where he helped facilitate partnerships between investors and accelerator programs. Laes is the founder of YoungTech Seattle, and his background includes mentoring and leadership roles at the University of Washington’s CoMotion and Techstars.

— Pranam Kolari, VP of search and recommendations at Coupang, is resigning from his role next month. Coupang is South Korea’s largest e-commerce platform and is headquartered in Seattle. Kolari, based in San Jose, Calif., was previously at Walmart Labs for nearly a decade where his roles included vice president of engineering for search.

— Datavault AI appointed Pete Scobell as VP of global security. The Beaverton, Ore.-based company helps businesses monetize their data and create digital twins of physical objects. Scobell is a decorated U.S. Navy SEAL veteran and will oversee Datavault AI’s security operations, risk management and asset logistics.

— Erin McHugh Saif, a former Massachusetts-based Microsoft executive, is CEO of an as-yet unnamed data and AI venture to serve “place-based partnerships,” which are networks of nonprofits, government agencies, and educational entities that aim to address education, jobs and housing needs.

“With better access to data, these organizations will leap ahead in this moment of AI transformation, gaining faster insight into which programs deliver the greatest improvement to significantly scale their impact,” Saif said on LinkedIn.

The effort has the support of the Ballmer Group, a philanthropic organization co-founded by former Microsoft CEO Steve Ballmer and his wife Connie, and the nonprofit TechSoup.

— Karen Ng was promoted to executive VP of product at HubSpot. Ng has been with the company since 2022, joining as senior VP of product and partnerships. Past employers include Common Room, Google and Microsoft, where she was chief of staff across the company’s developer tools business. Ng is based in the Seattle area.

Seattle and the Nordic nations have strong ties — from Norway’s first astronaut launching on a SpaceX mission to Scandinavian companies supporting the efforts to electrify the region’s ferries. And those connections stretch back more than a century when John Nordstrom, a Swedish immigrant, co-founded an eponymously named shoe store in Seattle’s downtown.

“As we look towards the future, we build on our history and also our heritage. But today, we reach for much more. We are partners in innovation, from high tech in the AI revolution to building more security projects,” said Anniken Huitfeldt, Norway’s ambassador to the United States.

On Tuesday evening, Huitfeldt helped kick off the annual Nordic Innovation Summit, held in Seattle’s Ballard neighborhood at the National Nordic Museum.

The event continues through Wednesday and features speakers and panelists discussing clean energy topics such as data center operations, microgrids and recycling; cyber security initiatives; innovation in biotech; and sustainable transportation.

“We’ve seen innovations come out of the summit,” said Seattle City Councilmember Dan Strauss, speaking Tuesday. “The ability to integrate technology into new business practices is something that has happened here before, and I’m excited to see it occur here again.”

Other speakers at the opening session included University of Washington Nobel Laureate David Baker, who shared new research published since he received his award from the Swedish institution one year ago. Baker is leading efforts that harness AI to create proteins that can be used in health care, environmental cleanup and other challenges.

Norwegian Astronaut Jannicke Mikkelsen livestreamed a presentation from Oslo to share the story of her journey to space, which began at age 10 when she had a devastating horse riding accident. During a five-year recovery, Mikkelsen became obsessed with NASA — even calling the agency’s Johnson Space Center seeking employment as a 12-year-old.

“It cost us a fortune,” she said. “My dad can’t afford to drive his car to work for a week because we can’t afford gas because I called the U.S. and I applied for a job.”

Mikkelsen ultimately pursued a career in 3D photography and 3D filmmaking, residing in Svalbard, a frozen tundra that ranks as one of the world’s northernmost inhabited areas.

“This is a place that equipped me the best to become an astronaut, because it’s sort of fear-based learning,” she said. “As soon as you leave town, any mistake you make could potentially kill you. It’s exceptionally cold. There is no communication to the outside world as you leave town.”

In March of this year, SpaceX — which has significant manufacturing operations in the Seattle region — launched Mikkelsen and three other non-governmental astronauts on the first crewed orbit over the Earth’s polar regions. The Fram2 mission spanned 3½ days. The astronauts performed scientific research, including data collection on the Northern Lights, which are beautiful but poorly understood and can destroy satellites.

Mikkelsen highlighted the importance of the collaboration between nations.

“We have four non-American astronauts on board an American spaceship. This, to me, just shows great trust that the U.S. showed in us,” she said. “But it’s also American technology that flew the first Norwegian astronaut into space.”

Speakers participating in the summit on Wednesday include Mathias Sundin, founder of the Warp Institute Foundation; Douglas Kieper, director of the Paul G. Allen Research Center; Nick Huzar, co-founder of OfferUp; Sunil Gottumukkala, CEO of Averlon; Petri Hautakangas, CEO of Tupl; Maiken Møller-Hansen, director of energy and sustainability for Amazon Devices; and other corporate, government and academic leaders.