Sequoia's managing partner Roelof Botha noted that there are currently 3,000 venture firms in the United States, while there were just 1,000 when he joined Sequoia 20 years ago.

Teller says X has a 2% hit rate, which means that most of the things the company tries don't work out, and that's okay.

Zoom CEO Eric Yuan says that, in a few years, we should be working a 3-4 day workweek because of AI.

Pytho AI wants to compress mission planning from days to mere minutes.

Strong by Form has designed a structural floor piece that can span longer distances than existing engineered wood, making it a replacement for steel or concrete. At the same time, the product is lighter than all three.

MacroCycle's approach to recycling dramatically reduces the amount of energy needed to produce new material, potentially lowering costs to the point where it could compete with virgin plastic.

Mbodi users prompt the software with natural language, and its cluster of AI agents works to make training easier.

Damoa pinpointed the problem: the complex, multi-step process moving a container from a ship to a freight train. He founded Glīd Technologies to try and solve it.

Waymo co-CEO Tekedra Mawakana believes the robotaxi company can increase road safety by reaching scale.

Waymo co-CEO Tekedra Mawakana opened up at TechCrunch Disrupt 2025 about the vandalism of its cars and how the company pushes back on government surveillance requests.

Large enterprises routinely buy more electricity than they use. COI Energy has a patented platform that lets them sell and share.

The company's so-called Pathfinder software can look at almost anything — buildings, tree-lined roads, even aerial views — and quickly match it to a database and generate real-time navigation.

“What we really do is we took the most constrained, complex, and costly medical imaging solution in radiology, and we supplanted it with what is the most accessible, simple and affordable, which is CT,” Sean Walsh, RADiCAIT’s CEO told TechCrunch. 

India-based Miraqules developed a nanotechnology that mimics blood clotting proteins to quickly stop heavy bleeding.

Although Maxim was convinced that gene therapy could reverse PKD, the biggest hurdle was creating a mechanism to deliver the drugs directly to the diseased cells.

If you’re not able to attend in person, the next best thing is to check out our livestream of the Disrupt Stage. Tune in right here starting at 10 a.m. PT.

These 20 companies are more than just early-stage startups — they’re the architects of what’s next. And they’ll have just six minutes on the Disrupt Stage to prove it.

Today is the first day of TechCrunch Disrupt 2025, where 10,000 founders, investors, and builders are flooding Moscone West for a nonstop run of ideas, demos, and deals. The energy is electric, the conversations are everywhere, and the breakthroughs are only just beginning. Don't miss out. Register here or head straight to Moscone West to join.

The countdown is almost over — tomorrow’s the day! In less than 24 hours, TechCrunch Disrupt 2025 takes over Moscone West.

With TechCrunch Disrupt 2025 right around the corner, we’re thrilled to introduce the companies hosting Side Events that will extend the buzz and excitement to the thousands of attendees and Silicon Valley locals alike.

The full Disrupt 2025 breakout session agenda is now live. Join for tactical, small-group learning on AI, fundraising, M&A, workflows, and more. Browse the full lineup and register today to save up to $444, and get 60% off a second pass before prices rise on October 27.

Just 3 days until liftoff for Disrupt 2025 — and the Space Stage is ready to explore the future of space tech (and every other frontier of innovation). Adam Maher (Ursa), Dr. Lucy Hoag (Violet Labs), and Dr. Debra L. Emmons (The Aerospace Corporation) will unpack how AI is transforming life in orbit. Register now to save up to $444 on your pass, and 60% on a second.

Three days. That’s it. TechCrunch Disrupt 2025 — the startup world’s biggest stage — kicks off October 27 – 29 at Moscone West in San Francisco. When Disrupt 2025 arrives, the city doesn’t just host innovation — it amplifies it, transforming San Francisco into a living showcase of ideas, products, and partnerships driving the next wave of tech. Register before prices hike in 3 days.